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PRP Hair Treatment | prp hair loss treatment before and after | Hair loss Treatment | prp treatment for hair loss | Platelet Rich Plasma

Platelet-rich plasma, also known as platelet-rich growth factors or platelet concentrate, is a concentrate of platelet rich plasma protein derived from whole blood, centrifuged to remove red blood cells.

PRP has become a popular treatment for many conditions in sport medicine, regenerative medicine, aesthetic medicine and hair loss treatment as it contains a variety number of growth factors and cytokines that can accelerate wound healing and tissue restoration.

Research also suggests that PRP injections can help treat androgenic alopecia (male pattern baldness).

PRP therapy process:

PRP therapy is a three-step process.

Most PRP therapy requires three treatments 4–6 weeks apart.

Maintenance treatments are required every 4–6 months.

Steps of PRP procedure:

A person’s blood is drawn, usually from the arm (approximately 10 to 60 mL).

Then, the whole blood is centrifuged in a centrifuge and divided into 3 layers, the bottom layer contains red blood cells (RBCs) with leukocytes the middle layer is the PRP, and the top layer is platelet-poor plasma (PPP)

The platelet-rich plasma is drawn up into a syringe and then injected into areas of the scalp that need increased hair growth.

Mechanism of action of PRP/ How does PRP work?

Many studies have demonstrated that platelets not only affect hemostatic system, but also affect inflammatory system, angiogenesis, stem cell induction, and cell proliferation through the release of many different growth factors and cytokines.

Activated platelets in PRP release numerous growth factors and cytokines which play a major role in stimulating hair growth through cell proliferation, differentiation and angiogenesis

Use of Platelet Rich Plasma in Hair Disorders

Androgenetic Alopecia (AGA):

Also called male pattern baldness.

FDA has approved oral finasteride (for men only) and topical minoxidil for the treatment of AGA.

Compared to minoxidil, finasteride, and adult stem cell-based therapy, 84% of all studies reported a positive effect of PRP.

In AGA, action of dihydrotestosterone on dermal papilla cells suppressed WNT signaling, resulting in defective hair growth and retarding hair cycling. PRP promoting hair growth by activating WNT/β-Catenin signaling lead to proliferation and differentiation of hair follicle cells and triggering new hair cycle.

Female pattern hair loss:

Most common cause of hair loss in middle-aged women.

The cause of this problem is unknown, but it is related to genetics, hormones, and environmental conditions.

Alopecia Areata (AA):

Common autoimmune disorder that causes non-scarring alopecia in males and females at any age.

Cicatricial Alopecia:

Type of scarring alopecia, caused by different inflammatory conditions, physical trauma, burn, or severe infections that lead to the destruction of the hair follicles and subsequent scarring.

Hair Transplantation:

Several studies have shown a beneficial effect of using PRP in combination with hair transplantation.

Adverse Effects of Platelet Rich Plasma:

Because PRP therapy involves injecting your own blood into your scalp, you aren’t at risk for getting a communicable disease.

Minimal adverse effects may include, temporary and tolerable pain during treatment, mild headache, minimal itching, transient erythema and edema on treated area.

PRP is not recommended if you:

are on blood thinners

are a heavy smoker

have a history of alcohol or drug misuse

You might also be rejected for treatment if you’ve been diagnosed with:

acute or chronic infections

cancer

chronic liver disease

chronic skin disease

hemodynamic instability

hypofibrinogenemia

metabolic disorder

platelet dysfunction syndromes

systemic disorder

sepsis

low platelet count

thyroid disease

If you’re concerned about hair loss, you have a number of options including medication & hair transplant surgery. Watch our video to know more about PRP for hair growth.

Talk to your doctor to see which treatment or combination of treatments is the best choice for you.

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Medical disclaimer: Medinaz Academy does not provide medical advice. The content available in our books and videos, on our website, or on our social media handles do not provide a diagnosis or other recommendation for treatment and are not a substitute for the professional judgment of a healthcare professional in diagnosis and treatment of any person or animal. We intend to provide educational information only. The determination of the need for medical services and the types of healthcare to be provided to a patient are decisions that should be made only by a physician or other licensed health care provider. Always seek the advice of a physician or other qualified healthcare provider with any questions you have regarding a medical condition.